| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85f67a0a358cbe53042dca4e1b6cf903
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e74277852f1aae0a3ff13f59a65456d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2014-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4e025d9682013ed9fa61a52b30a00e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5305a26c8876834bf87c8cdc6eae74fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0463d31e2e2b2d8448612f4d1a107fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cff15438150e999fc09e234fe055604b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_098f12b4b47ebc5b0736a500ea8ead3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f90268f3805e0fd10444482b0af35b60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e2aa8fcef6a743f133d2f59dd0e1472 |
| publicationDate |
2016-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016101258-A1 |
| titleOfInvention |
Method for detecting differentially methylated cpg islands associated with abnormal state of human body |
| abstract |
Disclosed is a method for detecting differentially methylated CpG islands associated with an abnormal state of a human body, characterized by detecting very minute amounts of methylated CpG short tandem nucleic acid sequences in highly fragmented DNA samples with genome scale, identifying differentially methylated CpG islands associated with abnormal state of human body and determining the corresponding abnormal state of human body. Sequencing libraries are constructed by using CpG short tandem sequences as primers to perform three steps of PCR reactions on DNAs which are conversed by modifiers, and detections of very minute amounts of methylated CpG short tandem nucleic acid sequences are implemented with high throughput sequencing technology. A group of genome sequences and methylation patterns of differentially methylated CpG islands which are associated with hepatocellular carcinoma are also disclosed; they may be used for distinguishing between hepatocellular carcinoma and non-cancerous state. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11566284-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11725251-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023066972-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11435339-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111154846-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662978-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11062789-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114072525-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662978-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634750-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11410750-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685958-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019060722-A3 |
| priorityDate |
2014-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |