| abstract |
The invention relates to a biohybrid for the use thereof in the regeneration of neural tracts, comprising an implantable tubular hybrid structure which is degradable and biocompatible and characterised in that it comprises three layers of different porosity: an inner layer a), an intermediate layer b) and an outer layer c), with continuity thereinbetween, the three layers consisting of the same porous hydrogel based on cross-linked hyaluronic acid. The invention also relates to a biohybrid comprising the hybrid tubular structure described, which can contain a fibrous material, preferably poly-L-lactic acid. The invention also relates to a method for producing said tubular hybrid structure and said biohybrid, and to the use of same for regenerating neural tracts in diseases that affect the central nervous system, preferably Parkinson's disease. |