http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016091272-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a415b93d7b075ff0b719494880d02235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ccc20614c90643dfbd6e964504e7d16 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0611 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 |
| filingDate | 2014-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_089c184cbcb4154f56243fead38ff8d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db6045118d7eea489c8bc4efc2603c69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_769bcd17945b8205807f50b5c202f2fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70fc2536c08bcc7590905adc898b1790 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_990470aa59cd6ad0341ea565f1aec63d |
| publicationDate | 2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016091272-A1 |
| titleOfInvention | System and method for establishing a long-term culture of avian primordial germ cells and uses thereof |
| abstract | The present invention provides a system and method for establishing a long-term culture of avian primordial germ cells and uses thereof. The invention is particularly useful to isolate and cultivate primordial germ cells from an early stage of avian embryos. In particular, the present invention provides a method for establishing a long-term culture of avian primordial germ cells, wherein the primordial germ cells are derived from germinal crescent tissue isolated from an avian embryo at stage 4 to 11, preferably at stage 4 to 10, more preferably at stage 6 to 10, even more preferably at stage 7 to 10. Accordingly, the present invention also provides a respective cell culture and cell line of avian primordial germ cells. The cultured avian primordial germ cells can be used for example to preserve the genetic diversity of avian species or as a targeting vehicle cell for genetic modification for disease resistance or other purposes, and to provide an interspecies or intraspecies germline chimera, e.g. for the purpose of propagation of endangered species in captive breeding programmes. Thus, the avian primordial germ cells can be genetically modified. Furthermore, the present invention also provides a method for maintaining a culture of avian primordial germ cells, as well as a germline chimera and a method for obtaining a germline chimera. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111500531-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116286612-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116286612-A |
| priorityDate | 2014-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.