abstract |
Provided are a cytidine derivative and an application thereof, having the general formula (I): the cytidine derivative has a growth inhibitory effect, confirmed by testing, on transplanted colon cancer HCT-116 tumors borne by nude mice, thus the cytidine derivative has high antitumor activity, while the impact on the body weight of the colon cancer HCT-116 tumor-bearing mice, as well as mortality rate data, prove the low toxicity of the compound. |