| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8df23dcb7fec40fb30564b7369302da3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01G45-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01G39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01G41-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01G49-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B17-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 |
| filingDate |
2015-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f5f1390cbbd2af71aad1b1ba9c17893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c96ca5fb99ad28883de3e2036f279282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_979791ab35404636483fc15b282bcf8a |
| publicationDate |
2016-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016077811-A1 |
| titleOfInvention |
Targeting intracellular copper ions for inhibiting angiogenesis using nanoparticles of ternary inorganic metal sulfide m1m2s4 (m1, independently, is mg, ca, mn, fe, or zn; m2=mo or w) compounds to treat metastatic cancer |
| abstract |
This invention describes a new type of covalent-network ternary inorganic metal sulfide compounds M 1 M 2 S 4 (M 1 , independently, is, Mg, Ca, Mn, Fe, or Zn; M 2 =Mo or W) and a process for preparing the biocompatible nanoparticles of such compounds. The nanoparticles are surface-modified with a capping agent and/or a biocompatible polymer and have the size from a few nanometers to several thousand nanometers. These nanoparticles are nontoxic and can be internalized by cells to deplete copper ions via a highly selective ion-exchange reaction between the intracellular copper ions and the divalent ion bound in the nanoparticles for the application of inhibiting angiogenesis in cancer and other diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3242670-A4 |
| priorityDate |
2014-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |