Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2391ebc02d0a2d863f4c0b1c72917a8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-65 |
filingDate |
2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3841fbc641011ec23f4cb3afd6ae55b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_016f6426df4ecdbe3e13b687af15a22a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6fedf4425bcb6cabba314a2dd7b38d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f23c8eaa0feec3576a7a6e5cc4010822 |
publicationDate |
2016-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2016077083-A1 |
titleOfInvention |
A high molecular weight biodegradable gelatin-doxorubicin conjugate |
abstract |
Disclosed herein are high molecular weight compounds comprising gelatin and doxorubicin, where the gelatin is covalently linked to doxorubicin through a cleavable linker. The cleavable linker can be cleaved under appropriate physiological conditions, and thus lead to the freeing of doxorubicin. The free doxorubicin can then exert its cytotoxic effects on cancer cells. Disclosed herein are methods of making the high molecular weight gelatin-doxorubicin conjugates and methods of use of the same. |
priorityDate |
2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |