| abstract |
The invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to the Ebola virus GP protein or neutralize infection of Ebola virus. The invention also relates to antigenic sites to which the antibodies and antigen binding fragments bind, as well as to nucleic acids that encode, and immortalized B cells and cultured plasma cells that produce, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and polypeptides recognized by the antibodies of the invention in screening methods as well as in the diagnosis, treatment and prevention of Ebola virus infection. |