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filingDate 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2016-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2016069760-A1
titleOfInvention Method of treating dementia by intranasal administration of vegf gene therapy
abstract Treatment of dementia (e.g. Alzheimers disease) using a polynucleotide agent (e.g. DNA or RNA) that contains a nucleotide sequence that encodes a vascular endothelial growth factor (VEGF) polypeptide. The polynucleotide agent is administered into the patients nose such that it is transported to the brain through or by way of neural pathways associated with the olfactory nerve. The polynucleotide agent may be contained inside a carrier vector, such as a viral vector.
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