| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fce3fba9d0ceb33f35257bcc38304203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efc947aa506c07913fc7b8c00a494118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd32bb110cbbd3891a2d0f9aa442ff97 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 |
| filingDate |
2015-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bfefdb0b07ececf775f8d5c8933ebe7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f19bd7a291201e0a5a73e099b7f07c5 |
| publicationDate |
2016-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016061296-A1 |
| titleOfInvention |
Pharmaceutical composition with improved stability |
| abstract |
The present invention provides an injectable composition for controlled release drug delivery and the process of making the same, where the composition comprises: a lactate-based polymer having a weight average molecular weight between 5,000 and 50,000 dalton, an acid number of less than 3 mgKOH/g and the content of residual lactide monomers in the lactate-based polymer of less than about 0.3% by weight; a pharmaceutically acceptable organic solvent; and a bioactive substance or a salt thereof that contains an amino acid serine in the molecular structure that is capable of reacting with lactide monomer to form a conjugate; and where the composition reduces the formation of the conjugate. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023012357-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020506232-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7074963-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110234336-A |
| priorityDate |
2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |