http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016050116-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fb423a5b676a3745ad96c64670b62da http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e383344737ce1c0fea94b5e5aedfb7e9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 |
filingDate | 2015-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebe2a5ae4b8e57bc7bb74efff7751196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44e7cb6cbd3daec759ee0a941767f928 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50d967543de3d197087cf8ad7c6a807e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd9a7a4b36fa20d6ae6541222af0b2cd |
publicationDate | 2016-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2016050116-A1 |
titleOfInvention | Abiraterone monosuccinate and preparation method therefor |
abstract | Disclosed are an abiraterone derivative, namely abiraterone monosuccinate, and a preparation method therefor. The abiraterone monosuccinate is as represented by formula (I). The preparation method therefor is: carrying out an esterification reaction of succinic anhydride and abiraterone as represented by formula (III) to obtain abiraterone monosuccinate. According to the present invention, an appropriate synthesis method is adopted to synthesize abiraterone monosuccinate efficiently and rapidly, the preparation method is moderate in reaction conditions, simple in posttreatment and suitable for industrial preparation, and provides a chemical entity source for follow-up medicinal chemical and clinical researches. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11559534-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10792292-B2 |
priorityDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.