http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016046833-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1fda4f6af8e73c9b8c7785ac548dc19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f321663caa70c069651bab3c051194b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_555d1481144634a776ec89114def5961 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
| filingDate | 2014-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2130276731fb5648efaf79ad5d7588da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e867bd6a525add7039ee3e301504e1b0 |
| publicationDate | 2016-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016046833-A3 |
| titleOfInvention | Improved processes for the preparation of agomelatine using novel intermediates |
| abstract | Provided herein are improved, commercially viable and industrially advantageous processes for the preparation of agomelatine, in high yield and purity, using novel intermediates. The process includes: a) reacting N-[2-(7-hydroxy-3,4-dihydro-1-naphthalenyl)ethyl] acetamide with a suitable activating agent; b) subjecting the acylated compound to aromatization by reacting with a suitable aromatizing agent; c) deprotecting the aromatized compound with a suitable deprotecting agent to produce the N-[2-(7-hydroxy-1-naphthalenyl)ethyl] acetamide; d) reacting the deprotected compound with a methylating agent to produce agomeltaine. |
| priorityDate | 2014-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.