| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3127c0ebee3f865b211b019fac84286 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58b8ba3e02a9dd71e958b5b2a3468093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf2154fed13404584c1803705230c07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb0d6db10c45d385ea1272d4f47d6cc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d9c4f35dbc4386bdbc07c2b9aff5658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d39f34a8ff67a1d443abd77d9c13ac8 |
| publicationDate |
2016-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016040790-A1 |
| titleOfInvention |
Supervised learning methods for the prediction of tumor radiosensitivity to preoperative radiochemotherapy |
| abstract |
Disclosed is a gene expression panel that can predict radiation sensitivity (radiosensitivity) of a tumor in a subject. A method of predicting radiation sensitivity is provided that is based on cellular clonogenic survival after 2 Gy (SF2) for 48 cell lines. Gene expression is used as the basis of the prediction model. The radiosensitivity cell-based prediction model is validated using clinical patient data from rectal and esophagus cancer patients that received RT before surgery. The radiosensitivity genomic-based prediction model identifies patients with rectal cancer that may benefit from RT treatment by assigning higher values of SF2 to radio-resistant patients and lower values of SF2 to radio-sensitive patients. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113450868-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113450868-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109346181-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109346181-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110957036-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110957036-B |
| priorityDate |
2014-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |