http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016038929-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_268be9afa00cf55b5aa72b1612151ecb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2015-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f873690b7796888d56a947fb9861aa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8403eee0ad0c5d9f347988d02ff6bed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_764d25260215d8a05e7e85187d5cb3c0 |
publicationDate | 2016-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2016038929-A1 |
titleOfInvention | Method for detecting presence/absence of fetal chromosomal aneuploidy |
abstract | A method for detecting the presence/absence of a fetal chromosomal aneuploidy, said method comprising a first amplification step for amplifying chromosomal DNA obtained from a biological sample that is collected from a pregnant woman to give a first amplification product, a second amplification step for multiplex amplifying a plurality of target regions with the use of the first amplification product as a template to give a second amplification product, a step for labeling both ends of the second amplification product to give a labeled second amplification product, a third amplification step for using a primer pair annealing to the labels and performing amplification with the use of the labeled second amplification product as a template to give a third amplification product, and a step for determining the base sequence and amplification amount of the target regions from the third amplification product, wherein the amplification in the first amplification step is 6,000- to 30,000-fold in terms of the total DNA amount, and the amplification in the second amplification step is 3- to 150-fold in terms of the total DNA amount. |
priorityDate | 2014-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.