| abstract |
The invention provides spray dried particles for inhalation, said particles consisting of (i) at least about 70% w/w of an alginate oligomer, (ii) at least about 10% w/w in total of a phospholipid and an anti-adherent compound, wherein said phospholipid is solid at room temperature, and wherein said phospholipid is present at no less than 0.5% w/w and said anti-adherent compound is present at no less than 0.5% w/w, and (iii) no greater than about 10% w/w of further excipients. The invention further provides a novel method for preparing said particles, capsules and dry powder inhalers comprising said particles and the therapeutic use of said particles, particularly in the treatment or prevention of a respiratory infection or a respiratory disorder. |