http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016023530-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d42b521e8808384189b18888e641d992 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-43504 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-00871 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2015-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c304d35e54e3feaea882e1a5e044930 |
| publicationDate | 2016-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016023530-A1 |
| titleOfInvention | Detection method using recombinant living cells for detecting xenobiotic substances and arrangement and test kit for performing the detection method |
| abstract | Known detection methods for foreign substances mark gene sequences of living cells and detect, in a spatially resolved manner, the translocation of the stably expressed marked fusion constructions within the recombinant cells under the influence of foreign substance. The detection method according to the invention utilizes the dynamic expression behavior of recombinant living cells and detects in an integral manner. The cell-inherent defense system is preferably used, wherein gene sequences a i -m i in recombinant cells (19) as a preferred means in a test kit for performing the detection method code for transporter proteins A i comprising fluorescent marker proteins M i as fusion constructs A i -M i . The cell-inherent defense system is activated under the influence of foreign substance. Transporter proteins A i that transport the foreign substance out of the living cells (19) are expressed in an increased manner. Together with the transporter proteins A i , the marker proteins M i are also expressed in an increased manner, which is optically detected and enables corresponding conclusions about the foreign substance (03). The detection method is preferably implemented by means of an arrangement (04) of genetically modified aquatic organisms (06) or living cells (19) thereof, which are permanently exposed in a water-permeable habitat tank (05) in an aquatic system (01) in the vicinity of a technical installation (02). |
| priorityDate | 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.