http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016015512-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0415418e3fc25468c06d4c897d8ea06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cc8e4f5a5a0f2c2dcec56ee6d50841f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d40285e27f4ed83b8728b0d477404958 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate | 2015-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0448ecedfff73c9ac3e80ba396d3902e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ec4b15d8956f31d74189fb6de7a539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d88fa8c7eac6f3e4fe597ea49697f11c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_038a2432b7f7f9c57646b00837ccb576 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_528e7d54041d31ae4c95ffbdec51611e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5294e0ca2ce3d81a5e9cf3196080da79 |
| publicationDate | 2016-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016015512-A1 |
| titleOfInvention | Method for synthesizing 25-hydroxy cholesterol |
| abstract | Disclosed is a method for synthesizing 25-hydroxy cholesterol. The method is as below: subjecting 24-dehydrocholesterol derivative as a raw material and a hydroxyl containing reagent to an addition reaction in the presence of a catalyst in an organic solvent, hydrolyzing the reaction product and separating to obtain 25-hydroxy cholesterol. The present invention adopts hydroxyl containing reagents such as water, formic acid, acetic acid, propionic acid, butyric acid, benzoic acid , p-methyl benzoic acid and etc. to replace the commonly used extremely toxic reagents such as Cr reagent, Hg reagent , multi-fluorinated acetone and etc. in the prior art. The raw materials of the present invention are easily available, and have low effect on environment. The operation and post treatment are convenient. Moreover, the method has the advantages of mild reaction conditions, simple operation, good selectivity, high efficiency, high yield, simple post-treatment, easy product separation, less three wastes and easy industrialization. |
| priorityDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 143.