abstract |
The present invention relates to a system for administering retinol to the skin, capable of ensuring the stability of retinol, reducing skin irritation caused by retinol and continuously exhibiting effects, and is characterized by a microneedle into which microparticles containing retinol or a retinol derivative are added. In addition, the present invention provides a preparation method for a system for administering retinol, capable of reducing skin irritation, exhibiting retinol effects for a long time and ensuring the stability of retinol which is very unstable with respect to light, moisture, temperature and the like. Additionally, the present invention provides a method for administering retinol to the skin, characterized by using the microneedle. |