http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016011524-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fc8c4f23758df7ed658973e2a913e38 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C04B40-06 |
filingDate | 2014-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc679c5e26cfb17772d6addac4941744 |
publicationDate | 2016-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2016011524-A1 |
titleOfInvention | Yin-yang gene expression ratio models for generation of clinical prognosis signatures for lung cancer patients |
abstract | A method for selection of a set of Yin genes and Yang genes for use in development of cancer patient prognosis, comprising: (i) screening gene expression data sets collected from a plurality of cancer tissue samples of patients to identify a first plurality of genes expressed in cancerous cells; (ii) screening gene expression data sets collected from a plurality of healthy subjects or cancer adjacent normal tissue samples to identify a second plurality of genes expressed in healthy cells; and (iii) selecting a set of Yin genes and a set of selected Yang genes using pathway and gene functional analysis; (iv) building a Yin and Yang gene expression ratio (YMR) model as a cancer prognosis signature. Implementing prognosis signature software for a cancer patient by: (v) detecting the expression values of selected Yin genes and selected Yang genes; and (vi) calculating the YMR for predicting the patient's clinical outcomes. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019243567-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112567052-A |
priorityDate | 2014-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.