http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016011438-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee602c630e57f59c6cfc1c1634e36064 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5032 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2015-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1cd0b0e36f85f3209c97e640044629d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6752a83f6708abc06e0212634b7993f |
| publicationDate | 2016-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016011438-A1 |
| titleOfInvention | Pericyte assay for transendothelial migration |
| abstract | A test animal for identifying blood vessel transendothelial migration-affecting factors or agents is described. The test animal comprises an implanted tissue mimicking model with a composite vascular structure comprising pericytes on test animal vasculature. The test animal can be used in a method of identifying or evaluating a blood vessel transendothelial migration-affecting agent that includes administering the agent to a test animal and determining the effect of the agent on the level of blood vessel transendothelial migration into or out of the tissue model. The test animal can also be used in a method of identifying or characterizing a metastasis-facilitating factor that includes administering or inducing circulating tumor cells in a test animal in which one or more factors in the pericyte have been silenced, and determining if the level of tumor cell migration into the tissue model has increased or decreased. |
| priorityDate | 2014-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 300.