Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1966f3c715acc0fa006db05d916301a7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-0105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01047 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-0105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01047 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-00 |
filingDate |
2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12c2dac4ea9deb986cbb5766af2eb4ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7ec620e6c0f3368a10849996c8d5dd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ce78406db79959f87d2555e813c4e16 |
publicationDate |
2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015197698-A2 |
titleOfInvention |
Novel method for biocatalytic whole cell reduction of dehydrocholic acid compounds, novel 7ss-hydroxy steroid dehydrogenase mutants and improved biocatalytic method for producing ursodesoxycholic acid |
abstract |
The invention relates to novel biocatalytic processes, comprising the whole cell reduction of dehydrocholic acid (DHCS) compounds, novel 7ß-hydroxysteroid dehydrogenase mutants, to the sequences encoding said enzyme mutants, to methods for producing the enzyme mutants and to the use thereof in enzymatic conversion of cholic acid compounds, and especially in the production of ursodeoxycholic acid (UDCS); The invention also relates to novel methods for the synthesis of UDCS using the enzyme mutants; and in particular to a further improved method for producing UDCS using recombined whole-cell biocatalysts. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-2020823-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018036982-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019209105-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110387360-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107980060-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017220486-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107980060-A |
priorityDate |
2014-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |