| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_327804b51d47ff6afc403138b838f3f5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2015-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7295b8f23ffd45c5e7389b444f80e2cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9293547bc2acb33fe60766746d2870a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df69f4d043833008b54b2f2ba333f2db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d51840bbe09a0e41d5663bdfec3c4d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b47f2d082492945d60777b81f862e618 |
| publicationDate |
2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015196944-A1 |
| titleOfInvention |
Gnrh analog-cytotoxic molecule conjugate and preparation method and use thereof |
| abstract |
Provided are a GnRH analog-cytotoxic molecule conjugate as shown by the following formula (I), and a preparation method and a use thereof in the preparation of drugs for treating tumours. The cytotoxic molecule is a taxol derivative or a docetaxel derivative. The conjugate can maintain the binding activity with GnRH receptors, and has a relatively good plasma stability and the growth inhibition activity on tumour cells. (X)Aaa 1 Aaa 2 -Aaa 3 -Ser-Aaa 5 -Aaa 6 (Y)-Leu-Aaa 8 -Pro-Aaa 10 -NH 2 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112717141-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112717141-B |
| priorityDate |
2014-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |