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filingDate 2014-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc8493467e8101ceb076e9168cd557fa
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publicationDate 2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2015193706-A1
titleOfInvention Method for alzheimer's disease drug screening and biomarker evaluation
abstract Octogon degus are the only rodents known to spontaneously develop an Alzheimer's disease (AD)-like neuropathology with hallmark pathological markers, such as amyloid-β (Αβ) plaques and tau hyperphosphorylation, and a concomitant age-related decline in cognition. Nevertheless, it is difficult to discriminate between healthy animals, and those developing the AD-like disease. The present invention is directed to identify individuals that will likely develop AD-like neuropathology. Also, the invention considers a method for drug screening of potentially beneficial compounds, and a method for identification of AD biomarkers.
priorityDate 2014-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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