| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2640066dcdbcabb59bd8fea4ef4bbb6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_806f0a3a49d26f0b2efb79a3ea184ce9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-11031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
| filingDate |
2015-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b788f6d9939d896538faa11fb6eaf9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74cb098895cf1cecf0ffc2076e557422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e0ec477333ca95849865ada995e5cc1 |
| publicationDate |
2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015193466-A1 |
| titleOfInvention |
Fluorescent amp-kinase biosensors |
| abstract |
The present invention deals with heterotrimeric AMP-activated protein kinase (AMPK) comprising a fluorophore pair wherein the conformational change can be measured by FRET. It represents an advanced tool to screen and identify AMPK interactors in vitro and in cells in vivo . Such invention can also be considered as a reporter of the cellular energy status as it allows the spatiotemporal monitoring, in situ , of fluctuations in the ratio of AMP and ADP versus ATP. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10640766-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018191322-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018191323-A1 |
| priorityDate |
2014-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |