http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015189769-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99505f5f312672820e9f78c254c00a4d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-56341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5608 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-563 |
| filingDate | 2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49166825ea68239799d6bfce2e0c79bf |
| publicationDate | 2015-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015189769-A1 |
| titleOfInvention | Mri method to quantify iron amount in tissues using diffusion magnetic resonance imaging |
| abstract | A method to quantify and map iron deposits in the brain with diffusion- weighted magnetic resonance imaging (MRI) is based on the differential sensitivity of mono-polar (MPG) gradient pulse diffusion sequences and bipolar (BPG) sequences on the local magnetic field gradients induced by iron deposits and their cross-term with the diffusion-encoding gradients. The method comprises the steps of acquiring (12, 14) first MRI images and second MRI of a Region Of Interest by using MPG and BPG sequences, providing (16) an attenuation model of the diffusion MRI attenuated signal representative of the observed tissue, estimating (18, 20) a first apparent diffusion coefficient ADCMPG and a second apparent diffusion coefficient ADCBPG by fitting the MRI images with the attenuation model, calculating (22) a an iron induced local gradient factor ξ Fe as (Formula I) (I), and determining (24) the concentration [Fe] and/or the amount of iron stored in the local zone of the tissue from the calculated iron induced local gradient factor ξ Fe . An apparatus is configured for implementing such a method. |
| priorityDate | 2014-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.