| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f28306adab6953d083eb8b65acbbad0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a04b5c901a7d3a01ce66f50db66f4c60 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-47 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2015-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_626fd2cbfa6fa69c23b7dbe8b00ecf0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ec945c5343971af61a27ff7de1798f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfebee2122c90c4199f6033b220c6c5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb763a43ab6ac6ad48e21cecd844a291 |
| publicationDate |
2015-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015189395-A1 |
| titleOfInvention |
Methods and compositions for diagnosing, monitoring and treating cancer |
| abstract |
The invention relates to methods for diagnosing cancer and determining the responsiveness to chemotherapyin a subject based on the detection of HSP70-expressing exosomes in a bodily fluid sample obtained from said subject. The invention also relates to methods for treating cancer and in particular methods for restoring or enhancing the anti-tumor immune response in a patient in need thereof by inhibiting the activation MDSC as well as methods for inhibiting or reducing HSP70-expressing exosomes-mediated tumor resistance against a chemotherapeutic agent and therefore methods for restoring or enhancing the efficacy of said chemotherapeutic agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017122131-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2020004436-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017139553-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7201961-B2 |
| priorityDate |
2014-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |