| abstract |
A method of producing a bacterial replication host for a bacteriophage is provided, including selecting a bacterial species, strain, serotype or isolate that is different to a pathogenic bacterium as a host for replication of the bacteriophage. The bacterial replication host provides a safe, efficient non-toxic vehicle for propagating bacteriophage that are capable of infecting a pathogenic bacterium that is of a different bacterial species, strain, serotype or isolate to the replication host. The pathogenic bacterium may be of the genus Vibrio, Aeromonas or Pseudomonas. Particular Vibrio bacteria are pathogens of shrimps or prawns, such as Vibrio parahaemolyticus . The invention may therefore have particular applicability to aquaculture. |