| abstract |
Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R 1 , R 2 , R 3 , R 4 , R 6 , Y 1 and Y 2 are as defined herein, and wherein at least one of R 3 or R 4 is a straight-chain C 1 -C 6 haloalkyl, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided. |