abstract |
Disclosed is a scaffold with a drug coating for preventing and treating restenosis, comprising a scaffold and a drug coating covering the surface of the scaffold. The active ingredients in the drug coating are guaiane sesquiterpene compounds P1, P2 and P3. P1 is Zedoalactone B, P2 is a stereoisomer of P1 and P3 is Zedoarondiol. The drug coating scaffold can inhibit the proliferation of endangium and inflammatory reactions of vascular walls after the scaffold is implanted, promote endothelialization of blood vessels and prevent forward thrombotic complications. |