http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015176175-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71d28a8ce0e41a167ed6064dd32d979c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-98 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-48 |
filingDate | 2015-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_208ec9b155b83a09dd0504d4575e40b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d48ed3cf6f19764c4fd2ffe481e9240 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c41d493d6f118717e8c3737c05f38972 |
publicationDate | 2015-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2015176175-A1 |
titleOfInvention | A continuous flow process for the preparation of ingenol-3-mebutate |
abstract | Disclosed is a continuous process for the preparation of ingenol-3-mebutate by reaction, in solution, of ingenol or ingenol anion and angelic anhydride or an equivalent angelylating agent. The continuous flow process is preferably performed in the presence of a base such as lithium hexamethyl disilazane (LiHMDS) and/or an activating agent such as dicyclohexylcarbodiimide (DCC). Also disclosed is a process for recycling the other reaction products obtained in the continuous process for preparation of ingenol-3-mebutate for formation of ingenol, which can then be recycled to form ingenol-3-mebutate. |
priorityDate | 2014-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 178.