http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015175638-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_457a7761bb0b0ae89f3bf95bbc5d08a6
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487
filingDate 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfe13cdb06d47a312e4162d856639c3e
publicationDate 2015-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2015175638-A1
titleOfInvention Selective analysis of modified biological molecules with solid-state nanopores
abstract In one aspect, methods are described herein for the selective detection and quantitative analysis of biological molecule compositions. A method described herein comprises providing a mixture comprising biological molecules, such as DNA, RNA or proteins, complexed with a translocating agent, such as another DNA or protein, and non-complexed biological molecules. The mixture is contacted with a membrane comprising at least one nanopore and an electric field is applied across the nanopore to selectively translocate the biological molecules complexed with the translocating agent through the at least one nanopore. Concentration of the complexed biological molecules is determined based on the translocation rate of said molecules.
priorityDate 2014-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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