| abstract |
In the present invention, stem cells in an unknown state of differentiation or cells that have been induced to differentiate from stem cells serve as test cells; culture supernatant is recovered from a culture plate of these test cells and a culture plate of control cells in a known state of differentiation, the culture supernatant being subjected to analysis by LC-MS or GC-MS; and the state of differentiation of the test cells is evaluated on the basis of the amounts of at least one compound selected from the group consisting of putrescine, kynurenine, cystathionine, ascorbic acid, riboflavin, pyruvic acid, serine, cysteine, threonic acid, citric acid, and orotic acid present in the culture supernatant of the test cells and the culture supernatant of the control cells, the amounts being determined as a result of the analysis. |