| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 |
| filingDate |
2015-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c1d57e0a9eee3622eee223086ad9f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6441a1a7d099e0e5ae3b7dfdb105d84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ce664f99c699ce85d12b632c2a434b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c33ed9b06bdeedbf9f5f8dc0df56087d |
| publicationDate |
2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015164481-A1 |
| titleOfInvention |
System and method for determination of ligand-target binding by multi-photon fluorescence anisotropy microscopy |
| abstract |
A multiphoton fluorescence anisotropy microscopy live cell imaging system and method to measure and map drug-target interaction in real lime at subcellular resolution. Proposed modality enables a direct measurement of drug/target binding in vivo , high -resolution spatial and temporal snapping of bound and unbound drug distribution, and presents an versatile tool to enhance understanding of drug activity. Application of tire system to measurement of intracellular target engagement of the chemotherapeutic Olaparib, a poly(ADP-ribose) polymerase inhibitor, in live cells and within a tumor in vivo . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108572163-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108572163-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021069428-A1 |
| priorityDate |
2014-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |