| abstract |
The invention relates to a selenium compound. Said selenium compound has formula (I), where R 1 = alkyl; R 2 = H, R 4 C(=0), R 4 OC(=0), a-aminoacyl, CH 3 SeCH 2 CH 2 CH(NH 2 )C(=0), CH 3 SeCH 2 CH 2 CH(OH)C(=0); X = OH, OR 3 , NH 2 , NR 4 R 5 , α-amino acid, CH 3 SeCH 2 CH 2 CH(COOH)NH-, CH 3 SeCH 2 CH 2 CH(COOH)0-; R 3 = alkyl; R 4 = alkyl, aryl; R 5 = H, alkyl, aryl; R 4 and R 5 which can together form a 5- or 6-membered cycloalkyl radical which can comprise a heteroatom; provided that when X = NH-terbutyl, R 2 ≠ C(=0)CH 3 . Said compound can be used as a pharmaceutical substance, in particular as an anitumour ssubstance. |