| abstract |
Apparatuses and methods for preparing an injection site on a target organ for enhanced delivery are described. In one embodiment, a drug delivery device, such as an injector, is supplied in a kit with an applicator for topically applied drugs, including anesthetics, vasodilators, and/or absorption enhancers. The applicator may be combined with another function, such as a needle or orifice cap. In another embodiment, the delivery system is supplied with an alignment ring, gripper, or vacuum cup to ensure the delivery device is in contact with and at the desired angle relative to the target organ, and ensures that the delivery device does not move relative to the delivery site during delivery. Also disclosed are topical applicators and topical formulations. |