abstract |
The present invention provides a compound that has a strong α7 nicotinic acetylcholine receptor (α7 nAChR)-regulating effect and is useful as a therapeutic drug for diseases associated with cholinergicity of the central nervous system (CNS) and/or peripheral nervous system (PNS), diseases associated with smooth muscle contraction, endocrine diseases, diseases associated with neurodegeneration, etc. Provided is a compound of formula (I) or a pharmaceutically acceptable salt of said compound [In the formula, X-Y-Z represents N-CO-NR 3A R 3B or the like, A represents an optionally substituted phenyl or the like, B represents optionally substituted imidazole or the like, R 2A , R 2B , R 2C , and R 2D may be the same or different and represent hydrogen atoms or the like, and R 3A and R 3B may be the same or different and represent optionally substituted C 3-10 cycloalkyls or the like]. |