http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015150551-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29505619a9d2567cd31bfe611242d002 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaeae0182dd6f2f78572f5903f31e327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcee26645d437cf31d786d940b15e15d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3e48baecea9d830f01e4e7b0e29db41 |
publicationDate | 2015-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2015150551-A1 |
titleOfInvention | A method of predicting phenotypic instability in a cell |
abstract | A method for predicting the phenotypic stability of a cell line comprises the steps of culturing the cell line over an assay period, and generating an environmental response fingerprint for the cell line at a plurality of different time points over the assay period, wherein each environmental response fingerprint is generated by determining the environmental response of the cells in the presence of each of a plurality of chemical cell stressors. The plurality of environmental response fingerprints are compared to detect change in the environmental response fingerprint over the assay period. The level of change in the environmental response fingerprint over the assay period is indicative of the level of predicted phenotypic instability in the cell line. The environmental response may be growth response, productivity response, or another detectable environmental response. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10591463-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626436-B2 |
priorityDate | 2014-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.