| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_015b06914223e1628bc6a0b3d09dcde5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f28306adab6953d083eb8b65acbbad0a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70589
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1121
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70517 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0637
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-04 |
| filingDate |
2015-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a26c979711537bcaad17b857d4c502a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a391e097344d16fe400b19d3ec5c04a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2abc788c31b12fcf42c423f030f7aaa7 |
| publicationDate |
2015-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015150492-A2 |
| titleOfInvention |
An isolated donor mhc-derived peptide and uses thereof |
| abstract |
The invention relates to an peptide derived from a polymorphic region of donor MHC class II molecules which induces tolerance and thus prevents transplant rejection in a patient in need thereof. The invention relates to isolated peptide of length ranging between 11 and 16 amino acids comprising the amino acid sequence: SDVGEYR (SEQ ID NO: 1) or a function- conservative variant thereof for use as drug. The invention relates to an in vitro method for determining whether a transplanted patient is tolerant, comprising a step of determining the presence of CD8+CD45RC low Tregs in a biological sample obtained from said transplanted patient, wherein the presence of CD8 + CD45RC low Tregs is indicative of tolerance. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021045150-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10724001-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020120786-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019519197-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017042170-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018084731-A1 |
| priorityDate |
2014-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |