http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015149753-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fab5a78161702097f97524ce6e5cdcd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77e5a2a80a7ef52761cfa43694c15864 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0068 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
filingDate | 2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eddc0f9b4f4c2873a2efcb5d6581aad2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43b96bf556467b9505f51650ff2bd07a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ca9adbe362719a51a6e17d84031a974 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56bcc21bca19f15d44a3ad87feb98291 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_129eff1473ced0d86d9e2181c1ebbdf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eecbf37108a582fb08f8187c064c92e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbb673b5f98ff61f5781677739954ce0 |
publicationDate | 2015-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2015149753-A3 |
titleOfInvention | Physical self-organizing hydrogel system for biotechnological applications |
abstract | The invention relates to a physical self-organizing hydrogel system for biotechnological applications composed of a non-covalent network on the basis of a protein-ligand interaction, comprising a tetrameric protein as a protein and biotin or one of the derivatives thereof as a ligand, wherein biotin or one of the derivatives thereof is covalently conjugated to an end of a polymer chain of a linear or multi-arm synthetic polymer or of a single- or double-strand oligonucleotide and wherein the solid content in relation to the entire hydrogel is at least 3% and the conjugates are cross-linked by the tetrameric protein. In the hydrogel system, there is a mixture ratio as a molar equivalent ratio between the protein and the number of terminal biotinylated ends of the polymer chains in the biotin-polymer conjugate of 1:2 to 1:8. The hydrogel formation occurs with controlled kinetics on the basis of a protein-ligand interaction. The hydrogel system can be used for the cultivation and encapsulation of cells. |
priorityDate | 2014-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.