| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
| filingDate |
2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08e1d0ca05bd3fa3fdd31835890b8456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c7512555a127428a433b2f805778649
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_355fe4c6d1ab7ff52d2958f4c6ff43f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c83315e82f11ee702ce265fe0622745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da0ddc84fba65acb0272475710b86ba6 |
| publicationDate |
2015-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015143446-A1 |
| titleOfInvention |
Nanomedicine optimization with feedback system control |
| abstract |
A cost function is specified to optimize a combination of N drugs, where the cost function includes at least one phenotypic contribution corresponding to efficacy and at least one phenotypic contribution corresponding to safety, and at least one of the N drugs is a nanomaterial-modified drug, with N being 2 or more. In vitro or in vivo tests are conducted by applying varying combinations of dosages of the N drugs to determine the phenotypic contributions from results of the tests. The results of the tests are fitted into a representation of the cost function, and, using the representation of the cost function, at least one optimized combination of dosages of the N drugs is identified. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114329702-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114329702-B |
| priorityDate |
2014-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |