http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015143113-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd4294bce38f455e0ee39c21e1cfff6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-061 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-076 |
| filingDate | 2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c52947bc05dad61ff32574fc2831b9d |
| publicationDate | 2015-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015143113-A1 |
| titleOfInvention | Preparations of derived extracellular vesicles, assays, and methods to modify therapeutic outcomes using such preparations |
| abstract | A method for altering the properties of extracellular vesicles and exosomes for use in diagnosis and therapeutics is disclosed, through their production by primary cell culture under Applicant's specific controlled conditions. A mammalian ejaculate is provided and sperm therefrom are incubated, during which time aliquots are evaluated for production of vesicles engineered to contain the cargo of choice and targeted to the desired application through adjustment of the surface receptor complement. For example, vesicle-borne Fc receptors act as decoys to protect sperm from antibodies in the female tract and vesicles additionally deliver regulatory molecules to modulate tract function, enabling the ability to control release and to engineer sperm-derived vesicle/ exosome structures to be used in diagnosis of infertility and in production of sperm doses of superior performance. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113373110-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019108957-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018004145-A1 |
| priorityDate | 2014-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.