http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015142288-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5035 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2015-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6dc8ecd43fe4a88a7bb689a735a955c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a42550f9060b3d5eca71f5e29904ed6 |
| publicationDate | 2015-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015142288-A1 |
| titleOfInvention | METHOD FOR PREDICTING TOXICITY OF A COMPOUND BASED ON NUCLEAR FACTOR-κB TRANSLOCATION |
| abstract | There is provided a method of screening for toxicity of a compound. The method comprises contacting a test compound with a test population of cells in which nuclear factor (NF)-κB has not been activated prior to the contacting; determining nuclear localization levels of NF-κB in the test population subsequent to the contacting; and comparing nuclear localization levels of NF-κB of a control population that has not been contacted with the test compound. An increase in nuclear localization levels of NF-κB of the test population relative to the control population is indicative that the test compound injures the cells and/or induces a pro-inflammatory response and thus is toxic to the cell type used in the method. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108885204-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108885204-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017091147-A1 |
| priorityDate | 2014-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.