abstract |
The present invention refers to a prognosis method for determining the severity of autoimmune diseases, e.g. rheumatoid arthritis, spondyloarthritis and systemic lupus erythematosus, characterized in that said method detects certain genetic polymorphisms of the VIP gene found between rs35643203, rs71575932 and/or rs7755568. The method according to the invention is also useful for establishing a customized patient treatment. The invention relatse to the use of genetic polymorphisms of the VIP gene, described in the invention, as biomarkers of said diseases, as well as a kit comprising primers or probes for detecting said polymorphisms and the use thereof for the same purpose. |