http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015133803-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_859399bafbd8d83a24ec70c9755c3aae |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e9577dbc27b3a6959918ce115a1e38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2913201f6809688ccc0da2af348be631 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d55509f381def41ae3a18a3c1cf88dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6a61d8db2c6458b854dfbdc1fbda9a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6130d757e827dae1766b8974238243fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba8df2f408d298120fd9dd169a5df7ff |
publicationDate | 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2015133803-A1 |
titleOfInvention | 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro[3,4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid d-aspartate hydrates and an antibacterial pharmaceutical compositions comprising their hydrates |
abstract | The present invention relates to 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro[3,4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid D-aspartate hydrates and an antibacterial composition comprising their hydrates. The present invention provides stable zabofloxacin D-aspartate hydrates wherein adsorption and desorption of water hardly occur, and provides specifically zabofloxacin D-aspartate sesquihydrate. Because the zabofloxacin D-aspartate hydrates according to the present invention hardly absorb moisture, they have an outstanding physicochemical property. Therefore, the drugs comprising zabofloxacin D-aspartate hydrate of the present invention do not easily break, especially in its tablet form, and changes little in the content of the main ingredient, thus exhibiting an excellent pharmaceutical stability. |
priorityDate | 2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.