Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85b959d2100bb308fcf773d125a37ab8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-14022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-14051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-14031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-15 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56988 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 |
filingDate |
2015-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_390c35ee0c2490ff60b155061b83848f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d49fadaf72a84b999c05b58ade6a1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba239bf01a521d7851f5f37fa5f99e70 |
publicationDate |
2015-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015128394-A2 |
titleOfInvention |
Soluble and immunoreactive variants of htlv capsid antigen p24 |
abstract |
The invention concerns soluble and antigenic HTLV p24 variants that can be fused to chaperones and their use in diagnostic applications such as immunoassays for detecting antibodies against HTLV-I or HTLV-II in an isolated biological sample. In particular, the invention relates to a soluble HTLV-I or HTLV-II p24 antigen comprising either the N- or the C-terminal domain of p24 and lacking the other domain. Moreover, the invention covers recombinant DNA molecules encoding these HTLV-I and -II fusion antigens as well as their recombinant production using expression vectors and host cells transformed with such expression vectors. In addition, the invention focusses on compositions of these HTLV p24 antigens with HTLV gp21 antigen and on an immunoassay method for detection of HTLV antibodies using the antigens of the invention. Also the use of HTLV p24 antigens in an in vitro diagnostic assay as well as a reagent kit for detection of anti-HTLV-antibodies comprising said HTLV antigens is encompassed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102437995-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019512688-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7065781-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190006476-A |
priorityDate |
2014-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |