http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015126033-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y201-01043 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 |
| filingDate | 2014-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1ea1aff5c608d145996b2606a1bff9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a74731873f6ffa124f577731157cafd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b0c924fd96e4e6ecb401e9cd0e82e13 |
| publicationDate | 2015-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015126033-A1 |
| titleOfInvention | Composition for controlling stem cell pluripotency, containing lin28a methylation inhibitor, and method for screening for lin28a methylation inhibitor |
| abstract | The present invention relates to: a composition for controlling stem cell pluripotency, containing an LIN28A methylation inhibitor; and a method for screening for an LIN28A methylation inhibitor, and more particularly, to a composition for controlling embryonic stem cell pluripotency or an anticancer composition, which is a composition for controlling stem cell pluripotency or treating cancer, containing an inhibitor for controlling the methylation of the 135th lysine of LIN28A to be methylated by Set7/9, and a method for screening for the inhibitor, wherein the screening method comprises the steps of: (a) making a candidate material come into contact with cells into which the LIN28A gene is introduced; (b) measuring the methylation level of the 135th lysine of LIN28A; and (c) selecting an inhibitor for controlling the methylation of the 135th lysine of LIN28A. The method of the present invention can effectively screen for a material capable of controlling embryonic stem cell pluripotency or a material having an anticancer activity, and the inhibitor screened for by the method of the present invention controls embryonic stem cell pluripotency, and is thus effective in the preparation of an agent for treating stem cell differentiation disorders or cancer by inhibiting the growth of cancer cells. |
| priorityDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.