| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb141b396e502bfce986c491d722e401 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3092 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate |
2015-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22060389a0cb511671d510e3a46b20fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ad5a0962f43d3dac951abfd08d6708d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_829f5d1e2883994167f4ffef7505539d |
| publicationDate |
2015-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015120187-A1 |
| titleOfInvention |
Chimeric antigen receptors recognizing cancer-spevific tn glycopeptide variants |
| abstract |
Disclosed are binding proteins, or fragments thereof, that specifically binds to a cancer- specific glycosylation variant of a protein and to a second epitope on the same protein, to a different protein presented on the same cell, or to a different protein presented on a different cell, such as an encoded polypeptide binding to both a cancer cell and an activated T cell. Also disclosed are polynucleotides encoding such binding proteins, including polynucleotides comprising codon- optimized coding regions and polynucleotides comprising coding regions that are not codon- optimized for expression in a particular host cell. Also disclosed are methods of making the encoded polypeptide and methods of using the polypeptide to treat, prevent or ameliorate the symptom of a disease such as cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11446398-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11186647-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10934363-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535677-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018028647-A1 |
| priorityDate |
2014-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |