Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b89abc7bb9a304bbf5709fab890f000 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b73f59c2bac775f8749ea0d8d7e2c1a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3437bf25b71953449e2ea9ba2acfce37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_745ecf23e55cd726d211e4daac2f07ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbd6bf9ccc7b2c740cb72f3b60eabcb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-145 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate |
2015-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ef9e62643e670c441001ca263be123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f0ddf09fe23fe86a8d79aa87567af87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc55a47e37a24283c451d086b2fae7a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_651d334cbee9488b8d0a6ebeb88d44cb |
publicationDate |
2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015116874-A1 |
titleOfInvention |
Recombinant microorganisms and methods of use thereof |
abstract |
The invention provides a carboxydotrophic acetogenic bacterium comprising a disrupting mutation in a lactate biosynthesis pathway enzyme and a method of producing a product by culturing the bacterium in the presence of a substrate comprising carbon monoxide. Preferably, the lactate biosynthesis pathway enzyme is lactate dehydrogenase (LDH) or another enzyme that converts pyruvate to lactate, wherein the disrupting mutation reduces or eliminates the expression or activity of the enzyme such that the bacterium produces a reduced amount of lactate or no lactate. |
priorityDate |
2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |