Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f294652e0d6df10315d7e73c355e5e6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62f9e41aa0b910b4bd3b5cfffc5659c1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2015-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e28596f2b0c2f2b3e3c8e3e191210aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2bc57094e42e22575ba0858d6aea3b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97ee992e8ceb67cec860a3755d0a1a9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f749144f957968c29e706947a1fe66e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0e4657af31be21d9ed73c0f577b3a7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86544e0a8a2908c89dc4129691b21669 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9bc44104158bec2f1029430146086a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fe397a3f84ecbd2a12ef0fc17d54e5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af6b5c41027a362e2bf20e2250e272e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d753c595837245d5cb61deefe9474b39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1088685c99c5ad3109abb6a55054596a |
publicationDate |
2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015114574-A1 |
titleOfInvention |
Preimplantation assessment of embryos through detection of free embryonic dna |
abstract |
The invention provides an in vitro method for non-invasive preimplantation assessment of an embryo by comprising amplifying and detecting a nucleic acid sequence of interest indicative of a genetic deficiency from a sample taken from the in vitro culture medium of the embryo and assessing the embryo as having a genetic deficiency if the presence of the sequence of interest is detected in the in vitro culture medium of the embryo. The examples show the detection of SNPs relating to the genes MDR1 and prothrombin and the SNP responsible for the Leiden syndrome. The application also mentions the possibility of establishing short tandem repeat (STR) marker profiles of DNA in the culture medium and full genome sequencing of the DNA in the culture medium as a means for determining embryo quality. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3205729-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109312349-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017065839-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018327821-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109536581-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109536581-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016351034-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I622651-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105368936-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3372690-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105368936-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021007403-A |
priorityDate |
2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |