Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18cec615665c2d98b045dedd27983927 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-664 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0623 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 |
filingDate |
2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16064832b9785361123ac17d90a825a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06e29b7fb0018a36729ad65eb4d1b229 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2ae61cf3368173b109caabef4f62b11 |
publicationDate |
2015-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015112311-A1 |
titleOfInvention |
Compositions and methods for inducing differentiation of stem cells |
abstract |
Compositions and methods for inducing differentiation of stem cells such as cancer stem cells (CSCs), and increasing sensitivity of CSCs to at least one oxidizing agent in a subject include sulindac and/or epimers thereof. These sulindac-based compositions and methods are particularly useful for treating cancers such as glioblastoma (GBM) and for differentiating stem cells in vitro that can be used for cell replacement therapy in a subject in need thereof. |
priorityDate |
2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |