| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbb5383743e5e8566f247a9430639593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d0d2cc9469d570ce285324ebbc305f6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-0275 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-12 |
| filingDate |
2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9214bda79394c253f613dd09aa83732
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e3563a8eb7adfc5d6ada69eab42e450
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d610aa45ca77b0b9548efc4b9feadd35 |
| publicationDate |
2015-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015100025-A1 |
| titleOfInvention |
Cystic fibrosis treatment comprising nitric oxide |
| abstract |
One aspect of the invention provides a method of treating a subject diagnosed with cystic fibrosis, but not having a pathological bacterial coloniszation in either lung. The method includes administering gaseous nitric oxide at a concentration of between about 40 ppm and about 400 ppm to the subject's lungs wherein said nitric oxide is administered by inhalation, and further wherein said nitric oxide induces conformational change in the cystic fibrosis transmembrane conductance regulator (CFTR) in the cells of the lung of the subject. Another aspect of the invention provides a kit comprising: an apparatus for administering gaseous nitric oxide to a subject and instructions for administering the gaseous nitric oxide according to one or more of the methods described herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9670163-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701639-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017100731-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017130066-A1 |
| priorityDate |
2013-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |